The Mechanism Switching the Osteoclast From Short to Long Duration Bone Resorption

The current models of osteoclastic bone resorption focus on immobile osteoclasts sitting on the bone surface and drilling a pit into the bone matrix. It recently appeared that many osteoclasts also enlarge their pit by moving across the bone surface while resorbing. Drilling a pit thus represents on...

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Bibliographic Details
Main Authors: Jean-Marie Delaisse, Kent Søe, Thomas Levin Andersen, Aleksandra Maria Rojek, Niels Marcussen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.644503/full