Statins and risk of diabetes mellitus
Statins are competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, which reduces HMG-CoA to mevalonate, the precursor of cholesterol via squalene. Inhibition of HMG-CoA reductase results in a decrease in cholesterol production. Since 1987, when the United States Federal...
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| Format: | Article |
| Language: | English |
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Faculty of Medicine Trisakti University
2014-08-01
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| Series: | Universa Medicina |
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| Online Access: | https://univmed.org/ejurnal/index.php/medicina/article/view/3 |