Colchicine reduces lung injury in experimental acute respiratory distress syndrome.

The acute respiratory distress syndrome (ARDS) is characterized by intense dysregulated inflammation leading to acute lung injury (ALI) and respiratory failure. There are no effective pharmacologic therapies for ARDS. Colchicine is a low-cost, widely available drug, effective in the treatment of inf...

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Bibliographic Details
Main Authors: Jocelyn Dupuis, Martin G Sirois, Eric Rhéaume, Quang T Nguyen, Marie-Élaine Clavet-Lanthier, Genevieve Brand, Teodora Mihalache-Avram, Gabriel Théberge-Julien, Daniel Charpentier, David Rhainds, Paul-Eduard Neagoe, Jean-Claude Tardif
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242318