Multi-omics of in vitro aortic valve calcification

Multi-omics of in vitro aortic valve calcification

Heart valve calcification is an active cellular and molecular process that partly remains unknown. Osteogenic differentiation of valve interstitial cells (VIC) is a central mechanism in calcific aortic valve disease (CAVD). Studying mechanisms in CAVD progression is clearly needed. In this study, we...

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Bibliographic Details
Main Authors: Daria Semenova, Arsenii Zabirnyk, Arseniy Lobov, Nadezda Boyarskaya, Olga Kachanova, Vladimir Uspensky, Bozhana Zainullina, Evgeny Denisov, Tatiana Gerashchenko, John-Peder Escobar Kvitting, Mari-Liis Kaljusto, Bernd Thiede, Anna Kostareva, Kåre-Olav Stensløkken, Jarle Vaage, Anna Malashicheva
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
multi-omics
transcriptomics
proteomics
valve interstitial cells
calcification
aortic valve
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.1043165/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.1043165/full

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