The impact of telomere length on prostate cancer aggressiveness, genomic instability and health disparities

The impact of telomere length on prostate cancer aggressiveness, genomic instability and health disparities

Abstract The telomere repetitive TTAGGG motif at the ends of chromosomes, serves to preserve genomic integrity and chromosomal stability. In turn, genomic instability is a hallmark of cancer—implicating telomere disturbance. Prostate cancer (PCa) shows significant ancestral disparities, with men of...

Full description

Bibliographic Details
Main Authors: Ruotian Huang, M. S. Riana Bornman, Phillip D. Stricker, Ilma Simoni Brum, Shingai B. A. Mutambirwa, Weerachai Jaratlerdsiri, Vanessa M. Hayes
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Prostate cancer
Telomere length
Health disparity
Aggressive disease
African ancestry
Genomic instability
Online Access:https://doi.org/10.1038/s41598-024-57566-1

Internet

https://doi.org/10.1038/s41598-024-57566-1

Similar Items