Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice

Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice

Abstract Background Diabetes is a proinflammatory state. Fibrosis of the renal glomerulus is the most common cause of end-stage renal disease. Glomerulosclerosis is caused by the accumulation of extracellular matrix (ECM) proteins in the mesangial interstitial space. Mesangial cells are unique strom...

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Bibliographic Details
Main Authors: Ching-Chuan Hsieh, Chun-Liang Lin, Jie-Teng He, Meihua Chiang, Yuhsiu Wang, Yu-Chin Tsai, Chien-Hui Hung, Pey-Jium Chang
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Stem Cell Research & Therapy
Subjects:
Myeloid-derived suppressor cells
Immunotherapy
Fibronectin
Diabetic nephropathy
Online Access:http://link.springer.com/article/10.1186/s13287-018-0915-0

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http://link.springer.com/article/10.1186/s13287-018-0915-0

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