Blunted blades: new CRISPR-derived technologies to dissect microbial multi-drug resistance and biofilm formation

ABSTRACTThe spread of multi-drug-resistant (MDR) pathogens has rapidly outpaced the development of effective treatments. Diverse resistance mechanisms further limit the effectiveness of our best treatments, including multi-drug regimens and last line-of-defense antimicrobials. Biofilm formation is a...

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Bibliographic Details
Main Authors: Christopher Gager, Ana L. Flores-Mireles
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msphere.00642-23