The Price of Surviving on Adrenaline: Developmental Programming Responses to Chronic Fetal Hypercatecholaminemia Contribute to Poor Muscle Growth Capacity and Metabolic Dysfunction in IUGR-Born Offspring

The Price of Surviving on Adrenaline: Developmental Programming Responses to Chronic Fetal Hypercatecholaminemia Contribute to Poor Muscle Growth Capacity and Metabolic Dysfunction in IUGR-Born Offspring

Maternofetal stress induces fetal programming that restricts skeletal muscle growth capacity and metabolic function, resulting in intrauterine growth restriction (IUGR) of the fetus. This thrifty phenotype aids fetal survival but also yields reduced muscle mass and metabolic dysfunction after birth....

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Bibliographic Details
Main Authors: Rachel L. Gibbs, Dustin T. Yates
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Animal Science
Subjects:
adaptive fetal programming
developmental origins of health and disease (DOHAD)
fetal growth restriction
intrauterine growth restriction (IUGR)
low birthweight
metabolic programming
Online Access:https://www.frontiersin.org/articles/10.3389/fanim.2021.769334/full

Internet

https://www.frontiersin.org/articles/10.3389/fanim.2021.769334/full

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