Determining Whether Sex and Zygosity Modulates the Association between APOE4 and Psychosis in a Neuropathologically-Confirmed Alzheimer’s Disease Cohort

Determining Whether Sex and Zygosity Modulates the Association between APOE4 and Psychosis in a Neuropathologically-Confirmed Alzheimer’s Disease Cohort

Background: The APOE4 allele is a genetic risk factor for developing late-onset Alzheimer’s disease (AD). Previous work by our group revealed that female APOE4 homozygotes with Lewy body (LB) pathology were more likely to experience psychosis compared to female APOE4 non-carriers, whereas in males t...

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Bibliographic Details
Main Authors: Mila Valcic, Marc A. Khoury, Julia Kim, Luis Fornazzari, Nathan W. Churchill, Zahinoor Ismail, Vincenzo De Luca, Debby Tsuang, Tom A. Schweizer, David G. Munoz, Corinne E. Fischer
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Brain Sciences
Subjects:
Alzheimer’s disease
Lewy body
APOE
psychosis
neuropsychiatric
Online Access:https://www.mdpi.com/2076-3425/12/9/1266

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https://www.mdpi.com/2076-3425/12/9/1266

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