Co-Culture of <i>P</i>. <i>gingivalis</i> and <i>F</i>. <i>nucleatum</i> Synergistically Elevates IL-6 Expression via TLR4 Signaling in Oral Keratinocytes

Co-Culture of <i>P</i>. <i>gingivalis</i> and <i>F</i>. <i>nucleatum</i> Synergistically Elevates IL-6 Expression via TLR4 Signaling in Oral Keratinocytes

Periodontitis, characterized by persistent inflammation in the periodontium, is intricately connected to systemic diseases, including oral cancer. Bacteria, such as <i>Porphyromonas gingivalis</i> and <i>Fusobacterium nucleatum</i>, play a pivotal role in periodontitis develo...

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Bibliographic Details
Main Authors: Lucas Yáñez, Cristopher Soto, Héctor Tapia, Martín Pacheco, Javiera Tapia, Gabriela Osses, Daniela Salinas, Victoria Rojas-Celis, Anilei Hoare, Andrew F. G. Quest, Jessica Díaz-Elizondo, José Manuel Pérez-Donoso, Denisse Bravo
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
periodontitis
oral cancer
inflammation
co-culture
<i>Porphyromonas gingivalis</i>
<i>Fusobacterium nucleatum</i>
Online Access:https://www.mdpi.com/1422-0067/25/7/3611

Internet

https://www.mdpi.com/1422-0067/25/7/3611

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