Mas‐related G protein‐coupled receptor type D antagonism improves portal hypertension in cirrhotic rats

Abstract Splanchnic vasodilatation contributes to the development and aggravation of portal hypertension (PHT). We previously demonstrated that in cirrhosis, angiotensin‐ mediates splanchnic vasodilatation through the Mas receptor (MasR). In this study, we investigated whether the recently character...

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Bibliographic Details
Main Authors: Lakmie S. Gunarathne, Indu G. Rajapaksha, Stephen Casey, Tawar Qaradakhi, Anthony Zulli, Harinda Rajapaksha, Jonel Trebicka, Peter W. Angus, Chandana B. Herath
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2022-09-01
Series:Hepatology Communications
Online Access:https://doi.org/10.1002/hep4.1987