Comparative and evolutionary analysis of the HES/HEY gene family reveal exon/intron loss and teleost specific duplication events.

Comparative and evolutionary analysis of the HES/HEY gene family reveal exon/intron loss and teleost specific duplication events.

BACKGROUND: HES/HEY genes encode a family of basic helix-loop-helix (bHLH) transcription factors with both bHLH and Orange domain. HES/HEY proteins are direct targets of the Notch signaling pathway and play an essential role in developmental decisions, such as the developments of nervous system, som...

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Bibliographic Details
Main Authors: Mi Zhou, Jun Yan, Zhaowu Ma, Yang Zhou, Nibras Najm Abbood, Jianfeng Liu, Li Su, Haibo Jia, An-Yuan Guo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3396596?pdf=render

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http://europepmc.org/articles/PMC3396596?pdf=render

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