Cellulose Nanofiber-Based Hydrogels Embedding 5-FU Promote Pyroptosis Activation in Breast Cancer Cells and Support Human Adipose-Derived Stem Cell Proliferation, Opening New Perspectives for Breast Tissue Engineering

Cellulose Nanofiber-Based Hydrogels Embedding 5-FU Promote Pyroptosis Activation in Breast Cancer Cells and Support Human Adipose-Derived Stem Cell Proliferation, Opening New Perspectives for Breast Tissue Engineering

The structure and biocompatibility analysis of a hydrogel based on cellulose nanofibers (CNFs) combined with alginate/pectin (A.CNF or P.CNF) and enriched with 1% or 5% 5-FU revealed more favorable properties for the cellular component when pectin was dispersed within CNFs. 5-Fluorouracil (5-FU) is...

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Bibliographic Details
Main Authors: Liliana-Roxana Balahura, Sorina Dinescu, Mihaela Balaș, Alexandra Cernencu, Adriana Lungu, George Mihail Vlăsceanu, Horia Iovu, Marieta Costache
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
5-fluorouracil
breast cancer
inflammasome
caspase-1
p53
tissue regeneration
Online Access:https://www.mdpi.com/1999-4923/13/8/1189

Internet

https://www.mdpi.com/1999-4923/13/8/1189

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