The miR-27a-3p/FTO axis modifies hypoxia-induced malignant behaviors of glioma cells

The miR-27a-3p/FTO axis modifies hypoxia-induced malignant behaviors of glioma cells

Glioblastoma multiforme (GBM) is one of the most malignant types of central nervous system (CNS) tumors. N6-methyladenine (m6A) RNA modification is a main type of RNA modification in eukaryotic cells. In this study, we find that the m6A RNA methylation eraser FTO is dramatically downregulated in gli...

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Bibliographic Details
Main Authors: Du Peng, Meng Li, Liao Xinbin, Liu Yi, Mo Xin, Gong Mengqi, Liao Yiwei
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2023-01-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
glioblastoma
m6A RNA methylation
FTO
miR-27a-3p
hypoxia
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023002

Internet

https://www.sciengine.com/doi/10.3724/abbs.2023002

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