Spleen tyrosine kinase (Syk) regulates systemic lupus erythematosus (SLE) T cell signaling.

Spleen tyrosine kinase (Syk) regulates systemic lupus erythematosus (SLE) T cell signaling.

Engagement of the CD3/T cell receptor complex in systemic lupus erythematosus (SLE) T cells involves Syk rather than the zeta-associated protein. Because Syk is being considered as a therapeutic target we asked whether Syk is central to the multiple aberrantly modulated molecules in SLE T cells. Usi...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Alexandros P Grammatikos, Debjani Ghosh, Amy Devlin, Vasileios C Kyttaris, George C Tsokos
Format: Artykuł
Język:English
Wydane: Public Library of Science (PLoS) 2013-01-01
Seria:PLoS ONE
Dostęp online:http://europepmc.org/articles/PMC3754955?pdf=render

Internet

http://europepmc.org/articles/PMC3754955?pdf=render

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