Metabolomics Analysis Reveals Deranged Energy Metabolism and Amino Acid Metabolic Reprogramming in Dogs With Myxomatous Mitral Valve Disease

Metabolomics Analysis Reveals Deranged Energy Metabolism and Amino Acid Metabolic Reprogramming in Dogs With Myxomatous Mitral Valve Disease

Background Myxomatous mitral valve disease (MMVD), a naturally occurring heart disease, affects 10% to 15% of the canine population. Canine MMVD shares many similarities with human MMVD. Untargeted metabolomics was performed to identify changes in metabolic pathways and biomarkers with potential cli...

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Bibliographic Details
Main Authors: Qinghong Li, Éva Larouche‐Lebel, Kerry A. Loughran, Terry P. Huh, Jan S. Suchodolski, Mark A. Oyama
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
amino acids
canine
congestive heart failure
dog
energy metabolism
heart failure
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.018923

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.018923

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