Structural Aspects of LIMK Regulation and Pharmacology
Malfunction of the actin cytoskeleton is linked to numerous human diseases including neurological disorders and cancer. LIMK1 (LIM domain kinase 1) and its paralogue LIMK2 are two closely related kinases that control actin cytoskeleton dynamics. Consequently, they are potential therapeutic targets f...
Główni autorzy: | , , , , |
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Format: | Artykuł |
Język: | English |
Wydane: |
MDPI AG
2022-01-01
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Seria: | Cells |
Hasła przedmiotowe: | |
Dostęp online: | https://www.mdpi.com/2073-4409/11/1/142 |