Free ISG15 Inhibits the Replication of Peste des Petits Ruminants Virus by Breaking the Interaction of Nucleoprotein and Phosphoprotein

Free ISG15 Inhibits the Replication of Peste des Petits Ruminants Virus by Breaking the Interaction of Nucleoprotein and Phosphoprotein

ABSTRACT Peste des petits ruminants virus (PPRV) causes a highly contagious disease in small ruminants and severe economic losses in developing countries. PPRV infection can stimulate high levels of interferon (IFN) and many IFN-stimulated genes (ISGs), such as ISG15, which may play a key role in th...

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Bibliographic Details
Main Authors: Jingyu Tang, Aoxing Tang, Nannan Jia, Hanyu Du, Chuncao Liu, Jie Zhu, Chuanfeng Li, Chunchun Meng, Guangqing Liu
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:Microbiology Spectrum
Subjects:
peste des petits ruminants virus
free ISG15
N0-P complex
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01031-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.01031-22

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