Targeted knockdown of PGAM5 in synovial macrophages efficiently alleviates osteoarthritis

Targeted knockdown of PGAM5 in synovial macrophages efficiently alleviates osteoarthritis

Abstract Osteoarthritis (OA) is a common degenerative disease worldwide and new therapeutics that target inflammation and the crosstalk between immunocytes and chondrocytes are being developed to prevent and treat OA. These attempts involve repolarizing pro-inflammatory M1 macrophages into the anti-...

Full description

Bibliographic Details
Main Authors: Yuhang Liu, Ruihan Hao, Jia Lv, Jie Yuan, Xuelei Wang, Churong Xu, Ding Ma, Zhouyi Duan, Bingjun Zhang, Liming Dai, Yiyun Cheng, Wei Lu, Xiaoling Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-024-00318-8

Internet

https://doi.org/10.1038/s41413-024-00318-8

Similar Items