The Protective Effect of Basic Fibroblast Growth Factor on Diabetic Nephropathy Through Remodeling Metabolic Phenotype and Suppressing Oxidative Stress in Mice

The Protective Effect of Basic Fibroblast Growth Factor on Diabetic Nephropathy Through Remodeling Metabolic Phenotype and Suppressing Oxidative Stress in Mice

Diabetic nephropathy is a common complication in diabetes, but still lack of effective therapeutic strategies. This study aimed to investigate the therapeutic effect of basic fibroblast growth factor (bFGF) in db/db mice with diabetic nephropathy and explore its possible metabolic mechanisms using a...

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Bibliographic Details
Main Authors: Tingting Wei, Qi Shu, Jie Ning, Shuaijie Wang, Chen Li, Liangcai Zhao, Hong Zheng, Hongchang Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
bFGF
diabetes
metabolomics
nephropathy
taurine
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00066/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00066/full

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