Ventral Midline Hysterectomy, Ovariectomy, and Ovariohysterectomy in Mus Musculus: A Surgical Protocol

Abstract Mice (Mus musculus) are one of the most commonly used animal species in basic science and translational research worldwide. Ovariectomy and hysterectomy are frequently employed to explore the systemic effects of the sex-hormone axis and other pathological conditions. While several surgical...

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Bibliographic Details
Main Authors: Peyton L. Nisson, Takuma Maeda, Hiroki Uchikawa, Oscar Cisneros, Michael T. Lawton, Tomoki Hashimoto
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-85203-y