<i>Clostridium botulinum</i> C3 Toxin for Selective Delivery of Cargo into Dendritic Cells and Macrophages
The protein toxin C3bot from <i>Clostridium botulinum</i> is a mono-ADP-ribosyltransferase that selectively intoxicates monocyte-derived cells such as macrophages, osteoclasts, and dendritic cells (DCs) by cytosolic modification of Rho-A, -B, and -C. Here, we investigated the application...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-10-01
|
Series: | Toxins |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6651/14/10/711 |