Notch Blockade Specifically in Bone Marrow-Derived FSP-1-Positive Cells Ameliorates Renal Fibrosis

Background: The infiltration of inflammatory cells during a kidney injury stimulates myofibroblast activation leading to kidney fibrosis. Fibroblast-specific protein 1 (FSP-1) positive cells have been reported as either myofibroblasts or monocytes during tissue fibrosis. The functions of FSP-1<su...

Full description

Bibliographic Details
Main Authors: Yongdong Wu, Ming Liang, Fengzhang Huang, Owen H. Cheng, Xiaoguang Xiao, Tae Hoon Lee, Luan Truong, Jizhong Cheng
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/2/214