Directed evolution and targeted mutagenesis to murinize <it>listeria monocytogenes </it>internalin A for enhanced infectivity in the murine oral infection model
<p>Abstract</p> <p>Background</p> <p>Internalin A (InlA) is a critical virulence factor which mediates the initiation of <it>Listeria monocytogenes </it>infection by the oral route in permissive hosts. The interaction of InlA with the host cell ligand E-cadh...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-12-01
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| Series: | BMC Microbiology |
| Online Access: | http://www.biomedcentral.com/1471-2180/10/318 |