Directed evolution and targeted mutagenesis to murinize <it>listeria monocytogenes </it>internalin A for enhanced infectivity in the murine oral infection model

<p>Abstract</p> <p>Background</p> <p>Internalin A (InlA) is a critical virulence factor which mediates the initiation of <it>Listeria monocytogenes </it>infection by the oral route in permissive hosts. The interaction of InlA with the host cell ligand E-cadh...

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Bibliographic Details
Main Authors: Hill Colin, Casey Pat G, Monk Ian R, Gahan Cormac GM
Format: Article
Language:English
Published: BMC 2010-12-01
Series:BMC Microbiology
Online Access:http://www.biomedcentral.com/1471-2180/10/318

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