Mechanistic Insights of Mitochondrial Dysfunction in Amyotrophic Lateral Sclerosis: An Update on a Lasting Relationship

Mechanistic Insights of Mitochondrial Dysfunction in Amyotrophic Lateral Sclerosis: An Update on a Lasting Relationship

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive loss of the upper and lower motor neurons. Despite the increasing effort in understanding the etiopathology of ALS, it still remains an obscure disease, and no therapies are currently available to h...

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Bibliographic Details
Main Authors: Niccolò Candelise, Illari Salvatori, Silvia Scaricamazza, Valentina Nesci, Henri Zenuni, Alberto Ferri, Cristiana Valle
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Metabolites
Subjects:
amyotrophic lateral sclerosis
motor neuron disease
mitochondria
metabolism
bioenergetic
Online Access:https://www.mdpi.com/2218-1989/12/3/233

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https://www.mdpi.com/2218-1989/12/3/233

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