Th1 cells contribute to retinal ganglion cell loss in glaucoma in a VCAM-1-dependent manner

Th1 cells contribute to retinal ganglion cell loss in glaucoma in a VCAM-1-dependent manner

Abstract Glaucoma is a complex neurodegenerative disorder characterized by the progressive loss of retinal ganglion cells (RGC) and optic nerve axons, leading to irreversible visual impairment. Despite its clinical significance, the underlying mechanisms of glaucoma pathogenesis remain poorly unders...

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Bibliographic Details
Main Authors: Chong He, Kun Peng, Xiong Zhu, Zuo Wang, Wenbo Xiu, Gao Zhang, Yang Chen, Chaonan Sun, Xiao Xiao, Donghua Liu, An Li, Yanping Gao, Jinxia Wang, Ping Shuai, Yilian Chen, Ling Yu, Fang Lu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Neuroinflammation
Subjects:
Glaucoma
Retinal neurodegeneration
Retinal ganglion cell
CD4+ T cells
VCAM-1
Th1 cells
Online Access:https://doi.org/10.1186/s12974-024-03035-5

Internet

https://doi.org/10.1186/s12974-024-03035-5

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