The role of immunotherapy in microsatellites stable metastatic colorectal cancer: state of the art and future perspectives

The role of immunotherapy in microsatellites stable metastatic colorectal cancer: state of the art and future perspectives

Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide, despite several advances has been achieved in last decades. Few prognostic and predictive biomarkers guide therapeutic choice in metastatic CRC (mCRC), among which DNA mismatch repair deficiency and/or microsatell...

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Bibliographic Details
Main Authors: Annalice Gandini, Silvia Puglisi, Chiara Pirrone, Valentino Martelli, Fabio Catalano, Simone Nardin, Andreas Seeber, Alberto Puccini, Stefania Sciallero
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
Subjects:
microsatellite stable
MSS
colorectal cancer
immunotherapy
checkpoint inhibitors
combination strategy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1161048/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1161048/full

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