Cholecystokinin Receptor-Targeted Polyplex Nanoparticle Inhibits Growth and Metastasis of Pancreatic Cancer

Cholecystokinin Receptor-Targeted Polyplex Nanoparticle Inhibits Growth and Metastasis of Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) remains the most aggressive malignancy with the lowest 5-year survival rate of all cancers in part owing to the lack of tumor-specific therapy and the rapid metastatic nature of this cancer. The gastrointestinal peptide gastrin is a trophic peptide that stimul...

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Bibliographic Details
Main Authors: Julian Burks, Sandeep Nadella, Abdullah Mahmud, Charoen Mankongpaisarnrung, Juan Wang, Jong-In Hahm, Robin D. Tucker, Narayan Shivapurkar, Stephan T. Stern, Jill P. Smith
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
CCK Receptor
Gene Therapy
Gastrin
Nanotechnology
Orthotopic
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X1830050X

Internet

http://www.sciencedirect.com/science/article/pii/S2352345X1830050X

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