Pharmacokinetics, pharmacodynamics, and safety of prandial oral insulin (N11005) in healthy subjects

Pharmacokinetics, pharmacodynamics, and safety of prandial oral insulin (N11005) in healthy subjects

AimsTo verify whether the oral insulin N11005 is administered as a prandial insulin by assessing the pharmacokinetics (PK), pharmacodynamics (PD), and safety profiles of N11005 with a short-acting biosynthetic human insulin (Novolin R) as reference.MethodsThis was a randomized, open-label, single-do...

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Bibliographic Details
Main Authors: Qi Pan, Xiaoxia Wang, Wenjia Li, Xiaofeng Chen, Yulei Zhuang, Qinghong Zhou, Yuhui Huang, Yijie Zhou, Li Lan, Zhijie Wang, Wenjia Wang, Juan Hong, Wei-Hua Hao, Yu-Tsai Yang, Lixin Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Endocrinology
Subjects:
oral insulin
pharmacokinetics
pharmacodynamics
safety
healthy subjects
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1172327/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1172327/full

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