Preclinical Safety Evaluation of Ophthalmic Viscosurgical Devices in Rabbits and a Novel Mini-Pig Model
Abstract Introduction To establish the preclinical safety and equivalency of ophthalmic viscosurgical devices (OVDs) comprised of bacterially sourced sodium hyaluronate (HA) to animal sourced HA using pyrogenicity and aqueous exchange models in rabbits and a novel mini-pig model to evaluate corneal...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Adis, Springer Healthcare
2019-02-01
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Series: | Ophthalmology and Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1007/s40123-019-0167-9 |