Direct cloning of a herpesvirus genome for rapid generation of infectious BAC clones

Introduction: The herpesviridae are DNA viruses with large and complicated genomes. The herpesvirus bacterial artificial chromosomes (BACs) have been useful for generating recombinant viruses to study the biology and pathogenesis. However, the conventional method using homologous recombination is no...

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Bibliographic Details
Main Authors: Hengxing Yuan, Yaoyao Zheng, Xiaoling Yan, Hailong Wang, Youming Zhang, Jingyun Ma, Jun Fu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Journal of Advanced Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S209012322200056X