Seeing or believing in hyperplexed spatial proteomics via antibodies: New and old biases for an image-based technology

Seeing or believing in hyperplexed spatial proteomics via antibodies: New and old biases for an image-based technology

Hyperplexed in-situ targeted proteomics via antibody immunodetection (i.e., >15 markers) is changing how we classify cells and tissues. Differently from other high-dimensional single-cell assays (flow cytometry, single-cell RNA sequencing), the human eye is a necessary component in multiple proce...

Full description

Bibliographic Details
Main Authors: Maddalena M. Bolognesi, Lorenzo Dall’Olio, Amy Maerten, Simone Borghesi, Gastone Castellani, Giorgio Cattoretti
Format: Article
Language:English
Published: Cambridge University Press 2024-01-01
Series:Biological Imaging
Subjects:
multiplex staining
dimensionality reduction algorithms
flow cytometry
image analysis
human vision
Online Access:https://www.cambridge.org/core/product/identifier/S2633903X24000138/type/journal_article

Internet

https://www.cambridge.org/core/product/identifier/S2633903X24000138/type/journal_article

Similar Items