Beclin-1 dependent autophagy improves renal outcomes following Unilateral Ureteral Obstruction (UUO) injury

Beclin-1 dependent autophagy improves renal outcomes following Unilateral Ureteral Obstruction (UUO) injury

BackgroundInterstitial Fibrosis and Tubular Atrophy (IFTA) is the most common cause of long-term graft failure following renal transplant. One of the hallmarks of IFTA is the development of interstitial fibrosis and loss of normal renal architecture. In this study, we evaluated the role of autophagy...

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Bibliographic Details
Main Authors: Reynold I. Lopez-Soler, Azadeh Nikouee, Matthew Kim, Saman Khan, Lakshmi Sivaraman, Xiangzhong Ding, Qun Sophia Zang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
autophagy
fibrosis
renal transplant
Beclin-1
kidney injury
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1104652/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1104652/full

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