Cellular-level analyses of SCN5A mutations in left ventricular noncompaction cardiomyopathy suggest electrophysiological mechanisms for ventricular tachycardia

Cellular-level analyses of SCN5A mutations in left ventricular noncompaction cardiomyopathy suggest electrophysiological mechanisms for ventricular tachycardia

Left ventricular noncompaction cardiomyopathy (LVNC) is a cardiovascular disease characterized by arrhythmia and heart failure. In this study, LVNC myocardial samples were collected from patients who underwent heart transplantation and were analyzed using exome sequencing. Approximately half of the...

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Bibliographic Details
Main Authors: Yanfen Li, Shenghua Liu, Jian Huang, Yuanyuan Xie, Aijie Hou, Yingjie Wei
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
SCN5A
Variant
LVNC
Arrhythmia
Tachycardia
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580824000177

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http://www.sciencedirect.com/science/article/pii/S2405580824000177

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