Head-to-Head Comparison of Modular Vaccines Developed Using Different Capsid Virus-Like Particle Backbones and Antigen Conjugation Systems

Head-to-Head Comparison of Modular Vaccines Developed Using Different Capsid Virus-Like Particle Backbones and Antigen Conjugation Systems

Capsid virus-like particles (cVLPs) are used as molecular scaffolds to increase the immunogenicity of displayed antigens. Modular platforms have been developed whereby antigens are attached to the surface of pre-assembled cVLPs. However, it remains unknown to what extent the employed cVLP backbone a...

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Bibliographic Details
Main Authors: Laurits Fredsgaard, Louise Goksøyr, Susan Thrane, Kara-Lee Aves, Thor G. Theander, Adam F. Sander
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Vaccines
Subjects:
vaccine
virus-like particle
conjugation system
vaccine design
modular vaccine platform
Online Access:https://www.mdpi.com/2076-393X/9/6/539

Internet

https://www.mdpi.com/2076-393X/9/6/539

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