Integrated Chemical Characterization, Network Pharmacology and Transcriptomics to Explore the Mechanism of Sesquiterpenoids Isolated from <i>Gynura divaricata</i> (L.) DC. against Chronic Myelogenous Leukemia

Integrated Chemical Characterization, Network Pharmacology and Transcriptomics to Explore the Mechanism of Sesquiterpenoids Isolated from <i>Gynura divaricata</i> (L.) DC. against Chronic Myelogenous Leukemia

Chronic myelogenous leukemia (CML) is a serious threat to human health, while drugs for CML are limited. Herbal medicines with structural diversity, low toxicity and low drug resistance are always the most important source for drug discoveries. <i>Gynura divaricata</i> (L.) DC. is a well...

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Bibliographic Details
Main Authors: Xinyuan Ye, Long Wang, Xin Yang, Jie Yang, Jie Zhou, Cai Lan, Fahsai Kantawong, Warunee Kumsaiyai, Jianming Wu, Jing Zeng
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceuticals
Subjects:
<i>Gynura divaricata</i> (L.) DC.
chronic myelogenous leukemia
molecular networking
sesquiterpenoids
network pharmacology
RNA sequencing
Online Access:https://www.mdpi.com/1424-8247/15/11/1435

Internet

https://www.mdpi.com/1424-8247/15/11/1435

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