Long noncoding RNA LINC00239 inhibits ferroptosis in colorectal cancer by binding to Keap1 to stabilize Nrf2

Long noncoding RNA LINC00239 inhibits ferroptosis in colorectal cancer by binding to Keap1 to stabilize Nrf2

Abstract Ferroptosis, a novel regulated cell death induced by iron-dependent lipid peroxidation, plays an important role in tumor development and drug resistance. Long noncoding RNAs (lncRNAs) are associated with various types of cancer. However, the precise roles of many lncRNAs in tumorigenesis re...

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Bibliographic Details
Main Authors: Yuying Han, Xiaoliang Gao, Nan Wu, Yirong Jin, He Zhou, Weijie Wang, Hao Liu, Yi Chu, Jiayi Cao, Mingzuo Jiang, Suzhen Yang, Yanting Shi, Xin Xie, Fulin Chen, Ying Han, Wen Qin, Bing Xu, Jie Liang
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05192-y

Internet

https://doi.org/10.1038/s41419-022-05192-y

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