Multi-omic insights into Parkinson's Disease: From genetic associations to functional mechanisms

Multi-omic insights into Parkinson's Disease: From genetic associations to functional mechanisms

Genome-Wide Association Studies (GWAS) have elucidated the genetic components of Parkinson's Disease (PD). However, because the vast majority of GWAS association signals fall within non-coding regions, translating these results into an interpretable, mechanistic understanding of the disease eti...

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Bibliographic Details
Main Authors: Brian M. Schilder, Elisa Navarro, Towfique Raj
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Neurobiology of Disease
Subjects:
Parkinson's Disease
Neurodegeneration
Genome-wide association study (GWAS)
Quantitative trait loci (QTL)
Multi-omics
Meta-analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121003296

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http://www.sciencedirect.com/science/article/pii/S0969996121003296

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