A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients.

A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients.

We initiated a prospective trial to identify transcriptional alterations associated with acquired chemotherapy resistance from pre- and post-biopsy samples from the same patient and uncover potential molecular pathways involved in treatment failure to help guide therapeutic alternatives.A prospectiv...

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Bibliographic Details
Main Authors: Hark Kyun Kim, Il Ju Choi, Chan Gyoo Kim, Hee Sung Kim, Akira Oshima, Aleksandra Michalowski, Jeffrey E Green
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3041770?pdf=render

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http://europepmc.org/articles/PMC3041770?pdf=render

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