Aptamer functionalized fluorescent probe for detection of thrombin in human serum via static quenching

Aptamer functionalized fluorescent probe for detection of thrombin in human serum via static quenching

Thrombin plays a pivotal role in blood coagulation, wound healing, and tumor metastasis. In this study, we developed a fluorescent probe (Apt15@QDs) by functionalizing quantum dots (QDs) with an aptamer 15 to specifically recognize thrombin. The aptamer Apt15 binds specifically to thrombin by adopti...

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Bibliographic Details
Main Authors: Penghui Hu, Ruiyan Huang, Jiangyue Ning, Haotian Chen, Zelong Yan, Hanmeng Wang, Li Ding, Chang Shu
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Arabian Journal of Chemistry
Subjects:
Thrombin
Quantum dots
Static quenching
Aptamer
Human serum samples
Online Access:http://www.sciencedirect.com/science/article/pii/S187853522300970X

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http://www.sciencedirect.com/science/article/pii/S187853522300970X

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