Coloured Rice Phenolic Extracts Increase Expression of Genes Associated with Insulin Secretion in Rat Pancreatic Insulinoma β-cells

Coloured Rice Phenolic Extracts Increase Expression of Genes Associated with Insulin Secretion in Rat Pancreatic Insulinoma β-cells

Glucose-induced oxidative stress is associated with the overproduction of reactive oxygen species (ROS), which may dysregulate the expression of genes controlling insulin secretion leading to β-cell dysfunction, a hallmark of type 2 diabetes mellitus (T2DM). This study investigated the impact of col...

Full description

Bibliographic Details
Main Authors: Gideon Gatluak Kang, Nidhish Francis, Rodney Hill, Daniel LE Waters, Christopher L. Blanchard, Abishek Bommannan Santhakumar
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
coloured rice
polyphenols
gene expression
pancreatic β-cells function
insulin secretion
type 2 diabetes
Online Access:https://www.mdpi.com/1422-0067/21/9/3314

Internet

https://www.mdpi.com/1422-0067/21/9/3314

Similar Items