Unlocking the mysteries of VLDL: exploring its production, intracellular trafficking, and metabolism as therapeutic targets

Unlocking the mysteries of VLDL: exploring its production, intracellular trafficking, and metabolism as therapeutic targets

Abstract Reducing circulating lipid levels is the centerpiece of strategies for preventing and treating atherosclerotic cardiovascular disease (ASCVD). Despite many available lipid-lowering medications, a substantial residual cardiovascular risk remains. Current clinical guidelines focus on plasma l...

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Bibliographic Details
Main Authors: Jingfei Chen, Zhenfei Fang, Qin Luo, Xiao Wang, Mohamad Warda, Avash Das, Federico Oldoni, Fei Luo
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Lipids in Health and Disease
Subjects:
Atherosclerotic cardiovascular disease
Very low-density lipoprotein
Low-density lipoprotein
LDL receptor-independent pathway
Online Access:https://doi.org/10.1186/s12944-023-01993-y

Internet

https://doi.org/10.1186/s12944-023-01993-y

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