Extracellular Alterations in pH and K+ Modify the Murine Brain Endothelial Cell Total and Phospho-Proteome

Extracellular Alterations in pH and K+ Modify the Murine Brain Endothelial Cell Total and Phospho-Proteome

Pathologies of the blood–brain barrier (BBB) have been linked to a multitude of central nervous system (CNS) disorders whose pathology is poorly understood. Cortical spreading depression (CSD) has long been postulated to be involved in the underlying mechanisms of these disease states, yet a complet...

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Bibliographic Details
Main Authors: Jared R. Wahl, Anjali Vivek, Seph M. Palomino, Moyad Almuslim, Karissa E. Cottier, Paul R. Langlais, John M. Streicher, Todd W. Vanderah, Erika Liktor-Busa, Tally M. Largent-Milnes
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceutics
Subjects:
blood–brain barrier
pH
proteome
phospho-proteome
endothelial
Online Access:https://www.mdpi.com/1999-4923/14/7/1469

Internet

https://www.mdpi.com/1999-4923/14/7/1469

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