Mechanistic Assessment of Anise Seeds and Clove Buds against the Neurotoxicity Caused by Metronidazole in Rats: Possible Role of Antioxidants, Neurotransmitters, and Cytokines

Mechanistic Assessment of Anise Seeds and Clove Buds against the Neurotoxicity Caused by Metronidazole in Rats: Possible Role of Antioxidants, Neurotransmitters, and Cytokines

Long-term use of the nitroimidazole-derived antibiotic metronidazole has been associated with neuronal damage due to its ability to cross the blood–brain barrier. Polyphenol-rich plants, such as anise seeds and clove buds, are suggested to have neuroprotective effects. However, their intracellular p...

Full description

Bibliographic Details
Main Authors: Amira M. El-Moslemany, Mai Hussein Abd-Elfatah, Nawal A. Tahoon, Rasha M. Bahnasy, Badriyah S. Alotaibi, Heba I. Ghamry, Mustafa Shukry
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Toxics
Subjects:
anise seeds
clove buds
metronidazole
brain injury
antioxidant markers
neurotransmitters
Online Access:https://www.mdpi.com/2305-6304/11/9/724

Internet

https://www.mdpi.com/2305-6304/11/9/724

Similar Items