The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids

The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids

Class III P-glycoproteins (Pgps) mediate biliary phosphatidylcholine (PC) secretion. Recent findings that class I P-glycoproteins are able to transport several short-chain phospholipid analogues raises questions about the role of these Pgps in physiological lipid transport. We investigated the bilia...

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Bibliographic Details
Main Authors: Charles M.G. Frijters, Coosje J. Tuijn, Roelof Ottenhoff, Bart N. Zegers, Albert K. Groen, Ronald P. J. Oude Elferink
Format: Article
Language:English
Published: Elsevier 1999-11-01
Series:Journal of Lipid Research
Subjects:
NBD-labeled lipids
canalicular membrane
bile formation
hepatobiliary lipid transport
ceramide
sphingomyelin
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520324184

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http://www.sciencedirect.com/science/article/pii/S0022227520324184

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