Environmental triggers of Parkinson's disease – Implications of the Braak and dual-hit hypotheses

Idiopathic Parkinson's disease (PD) may take decades to develop, during which many risk or protective factors may come into play to initiate the pathogenesis or modify its progression to clinical PD. The lack of understanding of this prodromal phase of PD and the factors involved has been a maj...

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Bibliographic Details
Main Authors: Honglei Chen, Keran Wang, Filip Scheperjans, Bryan Killinger
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121003508