Synergistic co-administration of docetaxel and curcumin to chemoresistant cancer cells using PEGylated and RIPL peptide-conjugated nanostructured lipid carriers

Synergistic co-administration of docetaxel and curcumin to chemoresistant cancer cells using PEGylated and RIPL peptide-conjugated nanostructured lipid carriers

Abstract Background A targeted co-administration system of docetaxel (DTX) and curcumin (CUR) using a PEG-modified RIPL peptide (IPLVVPLRRRRRRRRC)-conjugated nanostructured lipid carrier (P/R-NLC) was constructed to exert synergistic anticancer effects against chemoresistant breast cancer. Results D...

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Bibliographic Details
Main Authors: Chang Hyun Kim, Byoung Deok Kim, Tae Hwa Lee, Hyeon Kyun Kim, Min Jeong Lyu, Young In Yoon, Yoon Tae Goo, Myung Joo Kang, Sangkil Lee, Young Wook Choi
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cancer Nanotechnology
Subjects:
Synergistic
Anticancer
Breast cancer
Nano-lipid carrier
Drug evaluation
Growth inhibition
Online Access:https://doi.org/10.1186/s12645-022-00119-w

Internet

https://doi.org/10.1186/s12645-022-00119-w

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