(1)H-NMR spectroscopy revealed Mycobacterium tuberculosis caused abnormal serum metabolic profile of cattle.

To re-evaluate virulence of Mycobacterium tuberculosis (M. tb) in cattle, we experimentally infected calves with M. tb andMycobacterium bovisvia intratracheal injection at a dose of 2.0×10(7) CFU and observed the animals for 33 weeks. The intradermal tuberculin test and IFN-γin vitro release assay s...

Full description

Bibliographic Details
Main Authors: Yingyu Chen, Junfang Wu, Lingling Tu, Xuekai Xiong, Xidan Hu, Jiong Huang, Zhiguang Xu, Xiansong Zhang, Changmin Hu, Xueying Hu, Aizhen Guo, Yulan Wang, Huanchun Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3787013?pdf=render