Vascular endothelial growth factor induces the migration of human airway smooth muscle cells by activating the RhoA/ROCK pathway

Abstract Background Airway remodeling due to increased airway smooth muscle cell (ASMC) mass, likely due to enhanced proliferation, hypertrophy, and migration, has been proven to be highly correlated with decreased lung function in asthma patients. Vascular endothelial growth factor (VEGF) mediates...

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Bibliographic Details
Main Authors: Chengtian Lv, Yuwen Huang, Ruirong Yan, Yuanmei Gao
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Pulmonary Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12890-023-02803-y